Association of Elevated Oxidized Low Density Lipoprotein to Low Density Lipoprotein Ratio (Ox LDL/LDL) with Sub Clinical Atherosclerosis in Patients Receiving Maintenance Haemodialysis

نویسندگان

چکیده

Objective: To assess the oxidized low density lipoprotein (ox-LDL) to (LDL) ratio as an indicator of subclinical atherosclerosis in haemodialysis patients Methodology: This case control study was carried out at Jinnah Post Graduate Medical Center Karachi, from January December 2018. The were selected dialysis center (group B) whereas controls recruited normal healthy population A). access status atherosclerosis, doppler ultrasonography technique employed detect intima media thickness (IMT) common carotid artery subjects well controls. Lipid peroxidation detected by serum LDL levels. Results: mean group A 0.43±0.02, B samples 1.0±0.09. Ox-LDL/LDL 0.003±0.001. While Ox-LDL: 0.012±0.002. Ox-LDL found have a positive linear relationship with (r=0.8) group. Conclusion: is much enhanced on maintenance showing increased lipid peroxidation. has which marker sub clinical atherosclerosis. Early detection elevated will help nephrologists early and treatment

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ژورنال

عنوان ژورنال: Annals of Jinnah Sindh Medical University

سال: 2022

ISSN: ['2409-7381', '2523-1316']

DOI: https://doi.org/10.46663/ajsmu.v8i1.30-35